Repolarization Recipes for Atrial Fibrillation
نویسندگان
چکیده
منابع مشابه
Repolarization Recipes for Atrial Fibrillation
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, represents a major health burden to people and health care systems within the Western world (1). Given its increasing prevalence with age, coupled with the aging population, the number of Americans affected is expected to surge from approximately 2.3 million in the year 2000 to nearly 16 million by 2050 (2). Until recently,...
متن کاملDispersion of atrial repolarization in patients with paroxysmal atrial fibrillation.
UNLABELLED To study the role of the dispersion of atrial repolarization (DAR) in the genesis of atrial fibrillation (AF), monophasic action potentials (MAP) were recorded simultaneously from a catheter at the high lateral right atrium (HLRA) and a catheter moving around the high, middle and low lateral right atrium (RA) the high, anterior and posterior septal RA and the RA appendage in 15 patie...
متن کاملElectrocardiographic evidence of ventricular repolarization remodelling during atrial fibrillation.
AIMS Some atrial fibrillation (AF) patients develop excessive QTc prolongation and torsade de pointes when they take QTc-prolonging antiarrhythmic drugs (class IA/III) immediately after termination of AF. We hypothesized that this is caused by changes in ventricular repolarization during AF. We aimed to establish whether such 'ventricular repolarization remodelling' occurs. METHODS AND RESULT...
متن کاملDiscordant repolarization alternans-induced atrial fibrillation is suppressed by verapamil.
BACKGROUND Ventricular alternans of repolarization produces serious ventricular arrhythmias in experimental models. The present study investigated the role of alternans of atrial repolarization in patients with atrial fibrillation (AF). METHODS AND RESULTS Electrophysiological studies were performed in 19 patients without structural heart disease. Monophasic action potentials (MAP) were recor...
متن کاملArrhythmia/Electrophysiology Repolarization Alternans Reveals Vulnerability to Human Atrial Fibrillation
Background—The substrates for human atrial fibrillation (AF) are poorly understood, but involve abnormal repolarization (action potential duration [APD]). We hypothesized that beat-to-beat oscillations in APD may explain AF substrates, and why vulnerability to AF forms a spectrum from control subjects without AF to patients with paroxysmal then persistent AF. Methods and Results—In 33 subjects ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2012
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2011.12.010